Calmness is hidden in


Depression is a common illness worldwide!

At a global level, over 322 million people are estimated to suffer from depression.
Institute of Health Metrics and Evaluation. Global Health Data Exchange (GHDx).

What is Depression?

Depression has traditionally been identified as a mood or emotional condition that manifests itself in stages, according to research. This implies that regular emotional states alternate with depressive periods.

Many other titles have been used to characterize various varieties of depression: neurotic, reactive, or mild depression is one of the most commonly used clinical names, and because of their psychological basis, they are frequently thought to be treated by psychotherapy.

Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest.

Different Types of Depression:

Major Depressive Disorder

Includes symptoms of depression most of the time for at least 2 weeks that typically interfere with one’s ability to work, sleep, study, and eat.

Persistent Depressive Disorder

Includes less severe symptoms of depression that last much longer, typically for at least 2 years. (dysthymia)

Bipolar Disorder

Which is a severe form of depression where a person experiences psychosis symptoms, such as delusions (disturbing, false fixed beliefs) or hallucinations (hearing or seeing things that others do not see or hear).

Post Natal Depression

Occurs when a woman experiences major depression during pregnancy or after delivery (postpartum depression).

Premenstrual Dysphoric Disorder

A condition in which a woman has severe depression symptoms, irritability, and tension before menstruation. The symptoms of PMDD are more severe than those seen with PMS.

Seasonal Affective Disorder

Which comes and goes with the seasons, typically starting in late fall and early winter and going away during spring and summer.

Ferrari, F., & Villa, R. F. (2017). The Neurobiology of Depression: an Integrated Overview from Biological Theories to Clinical Evidence. Molecular neurobiology, 54(7), 4847–4865.

Comparison of PARI-FLO with monotherapy of imipramine

PARI-FLO® with methylfolate and other active ingredients have; antidepressant-like effect.

Based on the FST* test results, it was concluded that PARI-FLO® has antidepressant-like activity.

*FST: The Forced Swim Test as a Model of Depressive-like Behavior


Each component has been clinically proven.

Clinically proven

Its active ingredients are approved by the EMA.


GMP certified content prepared according to European standards.

Ease of use

With its suspension form, it provides easy absorption.

Combined formulation

It has been formulated strategically with the components that target the condition.


It has standardized contents. The amount of active ingredient in each dose is same.

Setonda Laboratorio

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