FAQ
Frequently Asked Questions
Recommendations for use
Pari-Flo recommended as a dietary supplement to the diet:
- with psychoemotional and psychosomatic disorders caused by stress, vegetative-vascular dystonia, arterial hypertension, hormonal disorders (menopause, premenstrual syndrome, hyperthyroidism, etc.)
- with depressive conditions
- with neuroses and neurasthenia of various genesis
- with increased irritability, states of fear, anxiety, anxiety
- with migraine attacks
- with convulsive syndrome against a background of neurological diseases and metabolic disorders
The forced swimming test is one of the most commonly used animal models for investigating the antidepressant-like effects of conventional drugs and herbal substances in mice and rats.
In a study with Imipramine and Pari-Flo, imipramine reduced the immobility times of animals as in other studies. As a tricyclic antidepressant, imipramine increased both swimming and climbing behavior, which may be due to its effect on noradrenergic and serotonergic pathways. Pari-Flo was also found to decrease the immobility time of mice as dose-dependent manner, which indicates an antidepressant-like effect.
Pari-Flo contains–active ingredients:
Passiflora Incarnata L., herba extractum, L-Glycine, L-Methylfolate, Magnesium L-Threonate
L-Methylfolate plus an antidepressant from the initiation of treatment may result in greater efficacy and more rapid improvement in depressive symptoms compared to standard antidepressant monotherapy.*
*Ginsberg LD, Oubre AY, Daoud YA. L-methylfolate Plus SSRI or SNRI from Treatment Initiation Compared to SSRI or SNRI Monotherapy in a Major Depressive Episode. Innov Clin Neurosci. 2011;8(1):19-28.